Renegade Kid's follow up to Dementium: The Ward is going to have a hard time getting people to pick up the box, especially the shoppers who browse the Nintendo DS section for Imagine Babyz and Pony Friends type fare.
But the first-person survival horror adventure crowd is probably going to adore Dementium II's box art, because having a hand attack you from inside your own mouth is proven to tickle the first-person survival horror bone. Sure, I suppose you could just bite down really hard in that situation, but when you're regurgitating an arm—a vicious arm intent on doing harm to your face—you're probably not capable of rational thought.
So we'll consider this box art a win, then.