Sony Computer Entertainment Japan's TGS presser revealed that the "Resident Evil 5: Director's Cut" will employ the Sony motion controller now under development. Here is video of that announcement, and the controller being used with the game.
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The gameplay begins at 2:50 (unless you speak Japanese, skip to that part, it's all presentation dialogue up to that) and lasts to the six-minute mark. It looks smooth enough, but the demonstrator also is holding a regular PS3 controller. Can't tell if that's because this is a prototype, or if that's how this game will be operated when it releases in the spring of 2010.
[TGS 09] PS3 モーションコントローラ バイオハザード5 [EyeToy] [YouTube via VG247]