Nintendo isn't normally in the business of publishing bloody, violent M-rated—or, in Japan's case, CERO D rated—games for its hardware. In fact, Zangeki No Reginleiv will likely be the first Wii game to carry such a high rating.
But blood shall flow and limbs shall be neatly severed in Zangeki No Reginleiv, a game announced way back in October 2008 and, so far, only for Japan. The game was originally known as Dynamic Zan, if that rings a bell. Should Nintendo bring the game to the Americas and Europe, we're guessing it's not going to be titled Dynamic Zan or Zangeki No Reginleiv.
The Wii game was developed by Sandlot, the team responsible for similarly violent action series Earth Defense Force for D3Publisher, so expect some familiar looking giant-thing slaying here. But also expect Wii MotionPlus and the Classic Controller support, as well as online cooperative multiplayer, should you ultimately get your hands on it.
You can officially color me a bright crimson hue of "interested."