Like they did with the Big Daddies, 2K have released some concept art for BioShock's tiniest denizens, the Little Sisters.
Unlike the first lot, which showed the initial designs for the original Big Daddies, these show how 2K Marin - the developers working on the sequel - have gone about depicting the Little Sisters for the second game. And they look...well, pretty much identical. Which I guess was the point!
She doesn't look mean. She just looks like she needs a nap.