Remember Me's creative director talks about the game's female protagonist, who caused some publishers to lose interest.
Sounds horrible but you have to see it from another angle, it's their money and they don't want to lose it. They're doing a game with a brownskinned woman and you can all see how "well" these games get received. Look at mirror's edge, asian woman with no big breasts, it sold terribly. We also just only discovered that women play video games so there aren't many that do yet.
I will be getting the game because it looks interesting, new and it's a cyberpunk!
EDIT: They should also use their female protagonist as marketing tool and put her more in the front. Show that the atypical protagonist is a strength of the game.