A social game version of No More Heroes for Japan's Mobage called No More Heroes Royal is incoming. NMH creator Goichi Suda said he aims to make the bloodiest social game. [Famitsu]
Well, it sucks that I'll never get to play this, but I really hope Suda 51 does something completely crazy with a No More Heroes social game.
I guess the easiest route is to make each player an assassin and task them with rising up to the top, but even then I have faith it'll be way more bizarre than that simple idea suggests.