The Sinister is a gaming controller...thing currently up on Kickstarter that looks, well, nothing like a gaming mouse.
The idea is similar to that of R.A.T.7, which got an A for effort but a C- for comfort. The Sinister looks to get around that by not being slightly customisable, but entirely customisable.
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You can pivot, rotate and slide the major components into any configuration you deem comfortable, and it's also got some fancy inputs that let it mimic either a PC mouse, keyboard controls or Xbox pad. It's also got haptic feedback.
Sinister [Kickstarter]