If there's a gaming equivalent to trick shots, not looking at the screen while playing would be one of them—and one that's all the more impressive when you're playing against another person.
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Watching Kayane here—one of the top Soul Calibur V players in the world—defeat her opponent without actually looking at the screen is pretty amazing. The video description says that she used the crowd's facial expressions to gauge what she should do—so she's still reacting to feedback. It's just not coming from the game.
Kayane plays without watching the screen / Kayane joue sans regarder l'écran @ Paris Manga 2013 [KayaneTV via EventHubs]