Like some other 360 titles like Dead Rising, Mass Effect 2 has tiny text, which users on small TVs and with poor eyesight are having trouble reading. Is BioWare going to fix the problem? Nope.
Just like Dead Rising, it's no easy fix, and since BioWare feel it affects only "a small portion of SDTV owners", they "are unable to resolve it for Mass Effect 2 through a title update".
If it makes those straining at the screen feel any better, the developer promises that the issue will be taken into consideration for future Mass Effect games, where HDTV owners can then complain that their displays are cluttered with giant text.