For the first time since 1991, a Madden game will not be released on Nintendo's primary/current home console.
A statement sent by EA to Nintendo World Report says:
We will not be releasing a Wii U version of Madden NFL in 2013. However, we have a strong partnership with Nintendo and will continue to evaluate opportunities for delivering additional Madden NFL products for Nintendo fans in the future.
Sure, you could point to this and say it's another blow for Nintendo's beleagured console, already suffering from a lack of third-party support. Madden is, after all, one of the biggest-selling games in the US.