Maybe it's through natural talent, maybe through hours of obsessively replaying something. Maybe it's speedrunning Metroid games, maybe hustling people in Street Fighter. Whatever it may be, what game are you best at, and how did you get that way?
Personally, I tend to find myself playing games as far as my natural skill will take me, and then soon after, moving on to the next game. It's a habit that's been exaggerated by the piles of games I go through now that I'm at Kotaku. Which makes me all the more fascinated by people who specialize in one game to the point that they can just destroy it.