AMBROV: X is an upcoming RPG that, while set in an established sci-fi universe (it's based on the Sime-Gen books), sure looks like an indie Mass Effect. Not that there's anything wrong with that.
Given how that series ended, and people's love for sci-fi, RPGs and decision-making (this has all three!), this might be able to catch a wave of interest, especially since they're saying they'll get the help of a famous former BioWare writer if their Kickstarter campaign hits, ahem, $750,000.
Jennifer Hepler, former writer on Dragon Age who was crushed by a wall of internet hate following Dragon Age 2's poor reception, has agreed to help out, even after seeing the obvious and calling the game a "complete Mass Effect rip-off".