The first all-new game given a trailer at the 2012 Video Game Awards is The Phantom Pain, and it seems almost deliberately confusing and vague. That's fitting given its premise, in which a veteran awakens in a hospital after a long coma, with his left hand amputated. In come the troops hellbent on exterminating the entire hospital population, and we can only guess it goes downhill from there. See for yourself.
No platform was specified, nor any planned release date. The developer is Moby Dick Studio, which seems to be a total newcomer, too.