Grand Theft Auto V will star three protagonists. All male. Here they are.
This comes courtesy the December cover of Game Informer, which you can see in its entirety here:
This news confirms what Kotaku reported last year: both that it will be set in Los Santos, Rockstar's take on Los Angeles, and that it will have more than one playable lead character. Grand Theft Auto V is slated for Spring 2013 on PS3 and Xbox 360.