I have not played Borderlands 2. But this gun—this delightfully obnoxious, bizarre gun—is actually kind of making me want to.
A gun that shouts at you, and can only be captioned as "annoying sounds?" That's the kind of silliness I appreciate in my games. Even if it makes me take off my headphones for a while.
Should you wish to have your own weaponry yell at you, according to PC Gamer the gun is name "Hyperion's Energizing Bane" and can be found in Lynchwood, late in the game. Our own Tina Amini adds that it sounds like Tiny Tina (no relation), and is a cursed weapon.
Cursed weapon, cursing weapon... all in good fun, right?