The PS3 exclusive title The Last of Us is being developed by Naughty Dog, the studio that brought us the Uncharted Trilogy.
The game's introductory trailer showed a young girl and an older man, presumably her father or some relative, fending off an invasion of deranged mutants infected by whatever pandemic that forms the game's backstory. The trailer will be familiar to those who played Dead Island. A sequence in which the girl hunts for ammunition indicates that it'll focus more on surviving than run-and-gun shooting.
Naughty Dog's co-president just tweeted that everything you see in the trailer was rendered in-engine within the game.