Yes, yes, Namco's February 2012 game Inversion will let you raise and lower the gravity of enemies and objects, letting you toss them and crush them. Plus the game includes zero-gravity combat and neat sequences that have enemies (or you!) running around on the walls and ceilings, as if up was down or right was down, etc.
All that's true, but I just wanted to show you that, thanks to all of that, you can throw grenades sideways in this game. Sideways.