Ridiculously easy for us of course. I'm sure when some neckbeard gets to $100,000 on "Who Wants to be a Millionaire" and goes deer-in-the-headlights when asked "Which Pope commissioned the painting of the Sistine Chapel ceiling," every snark on the art history blogs is all lolwut and SMFH and such.
Yes, "I don't think it's Climbman," either. Two, if not three of the bogus answers to "What was Mario's original name" could be ruled out on grounds that they sound like rejected Robot Masters from Mega Man. Which may make them sound all the more plausible, who knows!
Give the contestant credit, she doesn't use a lifeline, poll the audience, or cop out and take the already sizeable wad of cash she'd amassed ($43,100; getting $25,000 if she chose to answer and was incorrect.) Even with Meredith Viera staring at her like "are you shittin' me?" she dials in the focus, picks C and, I'm told, ended up with $250,000 after getting one more answer right.
Oh, and Pope Julius II commissioned the Sistine Chapel ceiling. Final answer.
Old School Nintendo Trivia on Millionaire [A Little Bit on the Awesome Side]