Answering the fan mailbag on the band's official site, Megadeth frontman Dave Mustaine says he's had recent "high level meetings" with Activision and Neversoft to discuss an idea that is more attractive to the band than a dedicated box set.
Here's Mustaine's reply to a fan's query about a potential Guitar Hero: Megadeth, a very popular question on their site:
I have recently had two very important high-level meetings with the people from Activision and Neversoft, and we are talking about a lot of things, but a Guitar Hero box set is not as attractive to me and the people from Guitar Hero as the new idea that they offered me, as the creative stuff that we are talking about is over-the-moon! I just hope that someone doesn't stand in the way of this happening. I know that there are a lot of really damaging results from our mothership (Warner) having some legal disputes with YouTube and Guitar Hero to name just a few.
Of course, Megadeth's songs have appeared in Guitar Hero, Guitar Hero II and Guitar Hero 5. And this clever fan-made video imagines a dedicated Megadeth game, although clearly that hasn't happened.