This actually could be a first. Comic erotic game W.L.O. Sekai Renai Kikou (World Love Organization) was released on personal computers this past March by Japanese developer Akabei Soft2. An Xbox 360 port has been announced. On breasts.
The text reads: "Celebrate! Xbox 360 Port Decided!!"
Akakei Soft2 announcing game on character's breasts? Talk about knowing one's audience.
The Xbox 360 port will certainly not be as graphic as the PC original.